Helping Hearts For Over 30 Years

Res-Q 1250+ Omega-3 & Vitamin D3 - 200 ct - Softgels

700 mg Combined EPA & DHA + 500 IU Vitamin D3 per Softgel
Res-Q 1250+ Omega-3 & Vitamin D3 - 200 ct Item #0128
Res-Q 1250+ Omega-3 & Vitamin D3 - 200 ct Quality Guaranteed
  • 700 mg EPA & DHA Omega-3
  • Fortified with 500 IUs Vitamin D3
  • Molecularly Distilled and Ultra Purified in Norway
  • No Fishy Aftertaste
  • Proud Member of GOED

Proud Member of GOED

Gluten Free Dairy Free Caffeine Free Non-GMO Norway Fish Oil Friend of the Sea

Doctor Testimonials

"Res-Q 1250+ is essential to our health. The pharmaceutical grade omega 3 fatty acid promotes heart health, eye health, brain health, and bone health. It also helps reduce total cholesterol levels. The addition of Vitamin D3 further promotes bone health. There is evidence that vitamin D helps prevent over twenty three types of cancers from occurring. I recommend Res-Q 1250+ to all of my patients."

–Dr. Eric Lebby, MD
Comments above are the opinion of the doctor quoted and may not be typical; results vary.

Res-Q 1250+ is a unique combination of ultra-purified heart healthy omega-3s and vitamin D3.* Designed to support your cardiovascular system, muscles, bones and overall body health.*


Res-Q 1250+ contains 700 mg of combined EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) omega-3s. Res-Q 1250+ undergoes an extensive purification process to ensure its safety* and purity, free of many types of contaminants. Each softgel contains 260 mg of EPA and 440 mg of DHA; two to three times the amount of heart healthy* omega-3s than many other brands.


Research indicates that vitamin D3 deficiencies may be related to osteoporosis and bone health, back pain, joint mobility and flexibility, depression, and other health issues.*The major role of vitamin D3 is to maintain normal blood levels of calcium and phosphorus. Vitamin D3 helps the body absorb calcium needed to form and maintain bones.

People who are at higher risk of having vitamin D3 deficiencies are the elderly and individuals with limited sun exposure.  Res-Q 1250+ has 500 IUs of Vitamin D3. 


We start with small fish caught in deep regions of the ocean. In a pharmaceutically licensed, Good Manufacturing Practices (GMP) certified facility in the fjords of Norway the oil is extracted and undergoes an extensive purification process including molecular distillation to removed any possible PCBs, dioxins and heavy metals, like mercury.

Each batch is independently three-party tested for purity from 250 possible toxic compounds by Eurofins one of the top toxicology labs in the world. Res-Q 1250+ is then encapsulated and bottled in the U.S.A.


Res-Q 1250+ contains Calamarine™ derived from calamari, a uniquely sustainable source of DHA omega-3. The fishing method for calamari produces no collateral harm to the surrounding ocean environment.

  • Highly selective unbaited hooks (hooklines)
  • Virtually no bycatch (other fish or living creatures caught unintentionally)
  • No impact on marine environments such as the ocean floor or coral reefs
  • Only harvest end-stage adults


A special antioxidant blend maintains the freshness inside each capsule and a natural lemon/lime flavor ensures a pleasant experience when taking Res-Q 1250+ omega-3 plus vitamin D3 softgels. No fishy aftertaste or fish burps! 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. It is recommended that a physician be consulted before taking any supplements. Results not typical and may vary.


  1. Berger et al. “Metabolic and nutritional support in acute cardiac failure.” Curr Opin Clin Nutr Metab Care. 2003 Mar; 6(2):195-201
  2. Nair SS, et al. “Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action.” J Nutr. 1997 Mar;127(3):383-93
  3. De Caterina R. et al. “Antiarrhythmic effects of omega-3 fatty acids: from epidemiology to bedside.”. Am Heart J. 2003 Sep;146(3):420-30
  4. Bucher HC, et al. “N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials.” Am J Med. 2002;112:298-304
  5. Supari F., et al. “Fish oil treatment decreases superoxide anions in the myocardium and coronary arteries of atherosclerotic monkeys.” Circulation. 1995 Feb 15;91(4):1123-8
  6. Richter WO., et al. “Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease.” Eur J Med Res. 2003 Aug 20;8(8):332-6
  7. Yli-Jama P. “Serum-free fatty acid pattern and risk of myocardial infarction: a case-control study.” J Intern Med. 2002 Jan;251(1):19-28
  8. Mozaffarian D, et al. “Effect of Fish Oil on Heart Rate in Humans…” Circulation. 2005 Sep 19 [Epub ahead of print]
  9. Paillard F. “Nutritional counseling for coronary and hypertensive patients.” Arch Mal Coeur Vaiss. 2003 Sep;96:27-33
  10. Armitage JA. “Increased blood pressure later in life may be associated with perinatal n-3 fatty acid deficiency.” Lipids. 2003 Apr;38(4):459-64
  11. Mori TA. et al. “Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans.” Hypertension. 1999;34:253-260
  12. Frenoux JM. et al. “A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats.” J Nutr. 2001 Jan;131(1):39-45
  13. Rousseau et al. “Dietary n-3 polyunsaturated fatty acids affect the development of renovascular hypertension in rats.”. Mol Cell Biochem. 2001 Sep;225(1-):109-19
  14. Morris MCB. “Does fish oil lower blood pressure? A meta-analysis of controlled trials.” Circulation 1993
  15. Curtis CL. “Effects of n-3 fatty acids on cartilage metabolism.” Proc Nutr Soc. 2002 Aug;61(3):381-9
  16. James MJ et al. “Dietary omega-3 fats as adjunctive therapy in a prototypic inflammatory disease: issues and obstacles for use in rheumatoid arthritis.” Prostaglandins Leukot Essent Fatty Acids. 2003 Jun;68(6):399-405
  17. Simopoulos AP. “Omega-3 fatty acids in inflammation and autoimmune diseases.” J Am Coll Nutr. 2002 Dec;21(6):495-505
  18. Cleland LG. “The role of fish oils in the treatment of rheumatoid arthritis.” Drugs. 2003;63(9):845-53
  19. Durrington PN, et al. “An omega-3 polyunsaturated fatty acid concentrate administered for one year decreased triglycerides in simvastatin treated patients with coronary heart disease and persisting hypertriglyceridaemia.” Heart. 2001;85:544–548
  20. “The effect of a diet enriched with omega-3 polyunsaturated fatty acids on the indices of the blood fibrinolytic system in patients in the initial stages of ischemic heart disease.” Kardiologiia. 1993;33(6):21-5
  21. Saynor R. et al. “The long-term effect of dietary supplementation with fish lipid concentrate on serum lipids, bleeding time, platelets, and angina.” Atherosclerosis. 1984 Jan;50(1):3-10
  22. Menendez JA. “Overexpression and hyperactivity of breast cancer associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues, but it is selectively inhibited by tumoricidal alpha-linolenic and gammalinolenic fatty acids…” Int J Oncol. 2004 Jun;24.)
  23. Nkondjock A. “Intake of specific carotenoids and essential fatty acids and breast cancer risk in Montreal, Canada.” Am J Clin Nutr. 2004 May;79
  24. Jordan A. “Effect of an omega-3 fatty acid containing lipid emulsion alone and in combination with 5-fluorouracil (5-FU) on growth of the colon cancer cell line Caco-2.” Eur J Nutr. 2003 Dec;42(6):324-31
  25. Hardman WE, et al. “Consumption of an omega-3 fatty acids product, INCELL AAFA, reduced side-effects of CPT-11 (irinotecan) in mice.” Br J Cancer. 2002;86:983-988
  26. Holness MJ. “Acute omega-3 fatty acid enrichment selectively reverses high-saturated fat feeding-induced insulin hypersecretion but does not improve peripheral insulin resistance.” Diabetes. 2004 Feb;53 Suppl 1
  27. Simoncikova P. “Comparison of the extrapancreatic action of gammalinolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected].” Endocr Regul. 2002 Nov;36 28. Shimura T. “Docosahexanoic acid (DHA) improved glucose and lipid metabolism in KK-Ay mice with genetic non-insulin-dependent diabetes mellitus (NIDDM).” Biol Pharm Bull. 1997 May;20
  28. Holness MJ. “Diabetogenic impact of long-chain omega-3 fatty acids on pancreatic beta-cell function and the regulation of endogenous glucose production.” Endocrinology. 2003 Sep;1
  29. “Resistance to Leptin Contributes to Obesity.” The Rockefeller University. 1997, Aug. 5
  30. Kruger MC, et al. “Calcium, gamma-linolenic acid and eicosapentaenoic acid supplementation in senile osteoporosis.” Aging (Milano).1998;10:385–394
  31. Albertazzi P, et al. “Polyunsaturated fatty acids. Is there a role in postmenopausal osteoporosis prevention?” Maturitas. 2002 May 20;42(1):13-22
  32. Terano T. “Effect of omega 3 polyunsaturated fatty acid ingestion on bone metabolism and osteoporosis.” World Rev Nutr Diet. 2001;88:141-7
  33. Högström, M et al. “n–3 Fatty acids are positively associated with peak bone mineral density and bone accrual in healthy men: the NO2 Study.” Am J Clin Nutr. 2007 85: 803-807
  34. Morris MC. “Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease.” Arch Neurol. 2003 Jul;60
  35. Hashimoto M. “Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer’s disease model rats.” J Neurochem. 2002 Jun;81
  36. Farooqu AA. “Plasmalogens, phospholipase A2, and docosahexaenoic acid turnover in brain tissue.” J Mol Neurosci. 2001 Apr-Jun;16.
  37. Malcolm Peet. “Essential fatty acids theoretical aspects and treatment implications for schizophrenia and depression.” Advances in Psychiatric Treatment 2002; 8 223-229
  38. Murck H. “Ethyl-eicosapentaenoate and dexamethasone resistance in therapy-refractory depression.” Int J Neuropsychopharmacol. 2004 Jun;:1-9
  39. Nemets B, et al. “Addition of Omega-3 Fatty Acid to Maintenance Medication Treatment for Recurrent Unipolar Depressive Disorder.” American Journal of Psychiatry 2002;159 477-479
  40. Tsekos E. “Perioperative administration of parenteral fish oil supplements in a routine clinical setting improves patient outcome after major abdominal surgery.” Clin Nutr. 2004 Jun;23
  41. Switzer KC. (n-3) Polyunsaturated fatty acids promote activation-induced cell death in murine T lymphocytes.” J Nutr. 2003 Feb;133
  42. Walton AJE, et al. “Dietary fish oil and the severity of symptoms in patients with systemic lupus erythematosus.” Ann Rheum Dis. 1991;50:463–466
  43. Cho E, et al. “Prospective study of dietary fat and the risk of age-related macular degeneration.” Am J Clin Nutr. 2001 Feb;73(2):209-18
  44. Seddon JM, et al. “Dietary fat and risk for advanced age-related macular degeneration.” Arch Opthalmol. 2001;119(8):1191-1199
  45. Seddon JM. “Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake.” Arch Ophthalmol. 2003 Dec;121(12):1728-37
Ingredients & Use

Supplement Facts

Serving Size: 1 Softgel         Servings per container: 200                                                                           Amount per serving	 % Daily Value* Calories (energy)  				15     Calories from fat   				10 Total Fat   					1.5 g 			  2%*
Polyunsaturated Fat  				1 g   			 †
Cholesterol    					<5 mg   		<2% Vitamin D (as D3 - cholecalciferol)  		 500 IU   		125%*   Omega-3 Fatty Acids    			750 mg		 †   EPA (Eicosapentaenoic Acid) 		260 mg    		†     DHA (Docosahexaenoic Acid)   		440 mg   		 †      Other Omega-3 Fatty Acids  		50 mg    		†       *Percent Daily Values are based on a 2,000-calorie diet.  † Daily Value not established.     Ingredients: Highly Refined and Concentrated Omega-3 Oil (calamari, anchovy, sardine), Capsule Shell (gelatin, glycerin and purified water), Natural Lemon/Lime Flavor, Proprietary Antioxidant Blend (consisting of rosemary extract, ascorbyl palmitate and Natural Tocopherols [soy]), Cholecalciferol.

Suggested Use

Adults take 4-6 capsules daily.


Customer Reviews

Res-Q 1250 really works Review by Robert
Davidsonville, MD; Age: 60-74; Medical Concern: Diabetes

I have been using this product for several years. It has significantly lowered my cholesterol and triglyceride levels which I have been able to maintain with daily use.

(Posted on 5/29/2016)

Results are the opinion of the reviewer and may not be typical.

It really works! Review by Andrew
Quakertown, PA; Age: 45-59

I've been taking the 1250+ for about three years. I used to experience atrial fibrillation a few times a week. Ever since I've been on the 1250+, I could count the number of times I've felt it on one hand.

It also helps a lot with joint pain, as I stand on concrete for 10-12 hours a day at work. I notice the difference the most when I don't take it for a day or two and so does my wife.

(Posted on 6/4/2015)

Results are the opinion of the reviewer and may not be typical.

Res-Q 1250+ Review by Barbara
Abingdon, MD

I have been taking this product for a few years. I love it, and recommend it to anyone. My last cold was two years ago.

(Posted on 2/12/2015)

Results are the opinion of the reviewer and may not be typical.

Good product. Review by Lorie
Lehighton, PA; Age: 45-59

We are happy with this product.

(Posted on 1/12/2015)

Results are the opinion of the reviewer and may not be typical.

User for long time. Review by Lois and Ralph
Mechanicsburg, PA

When the doctor put us on different statins, it got to be expensive and neither of us felt good on them. Stopped them and started the Res-Q products. Worked well and felt much better.

Been a user of Res-Q products for almost 20 years.

(Posted on 1/2/2015)

Results are the opinion of the reviewer and may not be typical.

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Why should I take Res-Q 1250+?

Res-Q 1250+ is designed to support general long-term health because it contains a balance of omega-3s, EPA and DHA as well as vitamin D3, which is the naturally occurring form of vitamin D. Res-Q 1250+ provides omega-3s with an EPA-to-DHA ratio of 1:1.75. This is achieved by combining Res-Q 1250 with Calamarine (DHA omega-3 oil extracted from calamari/squid).

What is Res-Q 1250+ and what makes it different?

Res-Q 1250+ is an omega-3 formula that contains vitamin D as cholecalciferol which is the naturally occurring form of vitamin D (vitamin D3). It also provides a 1:1.75 ratio of EPA-to-DHA omega-3 by combining Res-Q 1250 with Calamarine — DHA oil extracted from calamari.

Who should take Res-Q 1250+?

Anyone who is looking for a supplement that contains both EPA and DHA omega-3, plus vitamin D3, in the same softgel capsule. If you are currently taking Res-Q 1250 and a separate vitamin D supplement you may want to choose Res-Q 1250+.

How can I be sure Res-Q 1250+ is purified?

A product's Certificate of Analysis demonstrates that it meets requirements for purity.

Can I take Res-Q 1250 and Res-Q CalamarineTM together?

Yes. Both products contain EPA and DHA omega-3s and can be taken in combination; Res-Q Calamarine contains higher levels of DHA omega-3.

Are there any side effects in taking omega-3 fish oil?

Omega-3 fish oil is generally well tolerated. Everyone's body responds differently to natural supplements; results vary. Lower-grade fish oils have been known to cause upset stomach, and fishy breath. Better quality omega-3s often do not.

We always recommend reviewing supplements with your doctor prior to taking them. 

What makes Res-Q 1250+ eco-friendly and ocean-safe?

Res-Q 1250+ is partly derived from calamari. The fishing method for calamari produces no collateral harm to the surrounding ocean environment.

  • Highly selective unbaited hooks (hooklines)
  • Virtually no bycatch (other fish or living creatures caught unintentionally)
  • No impact on marine environments such as the ocean floor or coral reefs
  • Only harvest end-stage adults

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. It is recommended that a physician be consulted before taking any supplements. Results not typical and may vary.


Product Overview